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The IUP Journal of Biotechnology :
Phytochemical Screening and Antifungal Activity of Cyperus esculentus
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Cyperus esculentus L., a member of family Cyperaceae is an edible medicinal plant which is used for various ailments such as hypochondriasis, indigestion, nausea and fever. In the present study, the phytochemical screening and antifungal activity of various extracts (such as acetone, 50% ethanol (hydroethanol), chloroform and petroleum ether) of C. esculentus L. tubers were evaluated. The results showed the presence of various important secondary metabolites such as alkaloids, flavonoids, terpenoids, phenols, etc., in higher levels in hydroethanolic extract of the sample. Hydroethanolic and acetone extracts showed maximum antifungal activity against Candida albicans and Aspergillus flavus. Chloroform and petroleum ether extract showed maximum activity against A. flavus. Trichoderma sp. was known to be resistant against all the extracts of the sample.
 
 

Plants have almost limitless ability to synthesize aromatic substances, mainly secondary metabolites, of which at least 12,000 have been isolated, a number estimated to be less than 10% of the total. In many cases, these substances serve as the molecules of plant defense against predation by microbes, insects and herbivores. Further, some may involve in plant odour (terpenoids), pigmentation (tannins and quinines) and flavor (capsaicin). However, several of these molecules posses medicinal properties (Cowan, 1999).

Higher incidence of fungal infection caused by various species of fungi has been reported. Hence, research on bioactive principal substances that may lead to the discovery of new compounds is required. There has been a dramatic increase in the use of antifungal agents for the treatment of both systemic and local fungal infections. But the expanded use of antifungal agents has accelerated the development of resistance to antifungal drugs followed by frequent therapeutic failures and increasing mortality rate (Jorgenson et al., 1999).

Cyperus esculentus L. or tiger nutsedge is an annual or perennial herb growing up to 90 cm long with solitary stems growing from a tuber. According to ayurveda, the tuber is cooling, acrid, galactogue to the bowels, aphrodisiac, sharpens appetite and improves taste; useful in the treatment of eye troubles, burning sensations and leprosy; disturbs both heat production and heat regulation in the body (Jean, 1998).

 
 
 

Phytochemical Screening and Antifungal Activity of Cyperus esculentus, hypochondriasis, phytochemical screening, antifungal activity, aromatic substances, pigmentation, fungal infections, therapeutic failures, bioactive principal substances.