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  The IUP Journal of Biotechnology
Screening of Secondary Metabolitesand Antimicrobial Activity of Solanum viarum Dunal
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The present study was designed to evaluate the antibacterial activities and phytochemical profile of extracts from leaves of Solanum viarum. The in vitro antimicrobial activity was performed by agar disc diffusion method against bacteria, viz., Staphylococcus aureus, Klebisella pneumoniae, Escherischia coli, Pseudomonas aeruginosa and fungi, Aspergillus niger, Penicillium sp., Candida albicans. The n-butanol, methanol and aqueous extracts of fresh leaves of S. viarum showed maximum activity againstP. aeurginosa, followed by S. aureus and E. coli, among the organisms observed. Solanum viarum was observed to have antimicrobial activity and can be used for medicinal purposes.

 
 

Medicinal plants are nature's best gift to cure a number of diseases of men and animals. There are about 121 clinically useful prescription drugs worldwide that are derived from higher plants. About 70% of them came to the attention of pharmaceutical houses because of their use in traditional medicine (Abelson, 1990). The drugs used in indigenous system of medicines like Ayurveda in India has about 18,000 species of angiosperms, of which about 3,000 species are considered as important sources of medicinal and aromatic chemical compounds (Rajasekaran, 2001). In India, Tamil Nadu is at a strategic geographical location and possesses an invaluable treasure of medicinal plants holding a major share in the cultivation and export of the plant species Solanum sp. Medicinal plants are of great interest in the field of biotechnology as most of the pharmaceutical industries depend largely on the utilization of living plant cells for the production of pharmaceutical compounds, particularly for alkaloids, flavonoids, essential oils, steroids and terpenoids. Solanum viarum Dunal is an important medicinal plant belonging to the family Solanaceae, commonly known as `Medicinal solanum' or `Marunthu kathiri' or `Solanum khasianum' or `Soda apple', and serves as a supplementary source of steroidal raw material for industries in India. Solasodine, a steroidal compound obtained from berries and roots, is used as a substitute for diosgenin in the synthesis of steroidal hormones (Saini, 1966). It is also used in the manufacture of oral contraceptive tablets. The extracts also possess some nematicidal and bactericidal properties.

The leaves of S. viarum were collected from the agricultural fields of Coimbatore, India. The plant was identified and confirmed using standard manuals.

 
 
 

Biotechnology Journal, Antimicrobial Activity, Solanum Viarum, Leaf Extracts, Phytochemicals , Medicinal Plants, Steroidal Hormones, Bactericidal Properties, Antibacterial Principles, Fungal Cultures, Fungal Pathogenic Species, Phytochemical Analysis, Phenolic Compounds.